538904

Prostaglandin E₂

Involved in vasodilator actions of kinins such as bradykinin.

• 同義詞: Prostaglandin E₂, PGE₂
• 經驗公式（希爾表示法）: C₂₀H₃₂O₅
• CAS號碼: 363-24-6
• 分子量：: 352.47
• MDL號碼: MFCD00077861
• 分類程式碼代碼: 12352211
• NACRES: NA.77

屬性

• 品質等級: 100
• 描述: Merck USA index - 14, 7877
• 化驗: >98% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white to light yellow
• 溶解度: acetone: soluble; ethanol: soluble; ethyl acetate: soluble; methanol: soluble
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• SMILES 字串: OC1C(C(C(=O)C1)C\C=C\CCCC(=O)O)\C=C\C(O)CCCCC
• InChI: 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4+,13-12+
• InChI 密鑰: XEYBRNLFEZDVAW-RTYMFESYSA-N

描述

一般說明

Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC₅₀ = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.

生化／生理作用

Cell permeable: no

Primary Target
Involved in vasodilator actions of kinins such as bradykinin

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 25-50 µM inhibiting MAP kinase in rat mesangial cells

警告

Toxicity: Harmful (C)

其他說明

Li, X., et al. 1995. Am. J. Physiol.269, C986.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H360FD
• 防範說明: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• 危險分類: Acute Tox. 4 Oral - Repr. 1B
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3