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5.32586

Sigma-Aldrich

AEBSF hydrochloride

≥99% (HPLC), powder, serine protease inhibitor, Calbiochem®

同義詞:

AEBSF, HCl ≥99% by HPLC, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride, HCl

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About This Item

經驗公式(希爾表示法):
C8H10FNO2S · xHCl
CAS號碼:
分子量::
203.23 (free base basis)
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

product name

AEBSF, HCl ≥99% by HPLC,

化驗

≥99% (HPLC)

品質等級

形狀

powder

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
desiccated
protect from light

顏色

white

溶解度

H2O: 50 mg/mL

儲存溫度

2-8°C

InChI

1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H

InChI 密鑰

WRDABNWSWOHGMS-UHFFFAOYSA-N

一般說明

AEBSF >99%; 30827-99-7
Specific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K. A material with ≥97% purity by HPLC (Cat. No. 101500) & its InSolution is also available (Cat. No. 508436).
Specific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K. A material with ≥97% purity by HPLC (Cat. No. 101500) & its InSolution is also available (Cat. No. 508436).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

生化/生理作用

Primary Target
Serine proteases
Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Corrosive (L)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他說明

Citron, M., et al. 1996. Neuron17, 171.

Ohkubo, I., et al. 1994. J. Biochem.116, 1182.

Mintz, G.R. 1993. BioPharm.6, 34.

Lawson, W.B., et al. 1982. Folia Haematol.109, 52.

Markwardt, F., et al. 1974. Biochem. Pharmacol.23, 2247.
Markwardt, F., et al. 1973. Thromb. Res.2, 343.
Baker, B.R., and Cory, M. 1971. J. Med. Chem.14, 119.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Skin Corr. 1A

儲存類別代碼

8A - Combustible, corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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