524751-M

Phosphodiesterase 7A1, Human, Recombinant, S. frugiperda

• 同義詞: hPDE7A1
• 分類程式碼代碼: 12352203

屬性

• 重組細胞: expressed in baculovirus infected Sf21 cells
• 品質等級: 100
• 形狀: liquid
• 比活性: ≥0.5 U/μL
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; avoid repeated freeze/thaw cycles
• 儲存溫度: −70°C

描述

一般說明

Full-length, recombinant, human phosphodiesterdase 7A1 (PDE7A1) expressed in S. frugiperda insect cells using a baculovirus expression system. PDE7A1 is required for T-cell activation induced by the costimulation of CD3 and CD28 receptors. Increased PDE7A1 correlates with a decrease in cAMP, increased IL-2, and increased cell proliferation. Supplied as a partially purified preparation of catalytically active enzyme useful for inhibitor and activator assays.

警告

Toxicity: Standard Handling (A)

單位定義

One unit is defined as the amount of enzyme that is required to convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.

外觀

In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Han, P., et al. 2006. J. Biol. Chem.281, 15050.
Lugnier, C. 2006. Pharmacol Ther.109, 366.
Bloom, T.J., and Beavo, J.A. 1996. Proc. Natl. Acad. Sci. U S A93, 14188.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable