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重要文件

489350

Sigma-Aldrich

L-(–)-Norepinephrine-(+)-bitartrate

α,β-Adrenergic agonist.

同義詞:

L-(−)-Norepinephrine-(+)-bitartrate salt monohydrate, R(–)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol-(+)-tartrate, Noradrenaline

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About This Item

經驗公式(希爾表示法):
C8H11NO3 · C4H6O6 · H2O
CAS號碼:
分子量::
337.28
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

描述

Merck USA index - 14, 6695

化驗

≥97% (LC/MS)

形狀

crystalline solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
desiccated

顏色

white

溶解度

water: 1 mg/mL

運輸包裝

ambient

儲存溫度

2-8°C

SMILES 字串

NC[C@H](O)c1cc(c(cc1)O)O.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O

InChI

1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1

InChI 密鑰

LNBCGLZYLJMGKP-LUDZCAPTSA-N

一般說明

α,β-Adrenergic agonist. A vasoconstrictive agent that causes down-regulation of angiotensin II receptors. Oxidation sensitive.

生化/生理作用

Cell permeable: no
Primary Target
α,β-Adrenergic agonist
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

準備報告

Addition of sodium bisulfite (at a final concentration of 0.1%) is necessary to prevent oxidation.

重構

Following reconstituiton, refrigerate (4°C). Stock solutions are stable for up to 5 days at 4°C.

其他說明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Yang, H., et al. 1996. Hypertension 27, 1277.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 1 Dermal - Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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H Yang et al.
Hypertension (Dallas, Tex. : 1979), 27(6), 1277-1283 (1996-06-01)
Norepinephrine causes downregulation of angiotensin II (Ang II) receptors in Wistar-Kyoto rat (WKY) brain neuronal cultures. The aim of this study was to compare the cross talk between Ang II and alpha1-adrenergic receptors in these neuronal cultures. Norepinephrine causes a
Inbal Rachmin et al.
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Hair greying depends on the altered presence and functionality of hair follicle melanocytes. Melanocyte stem cells (MelSCs) reside in the bulge of hair follicles and give rise to migrating and differentiating progeny during the anagen phase. Ageing, genotoxic stress, redox

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