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74480

Sigma-Aldrich

去甲肾上腺素 盐酸盐

≥98.0% (sum of enantiomers, HPLC)

同義詞:

L-Arterenol hydrochloride, L-Noradrenaline hydrochloride

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About This Item

經驗公式（希爾表示法）:
C8H11NO3 · HCl
CAS號碼:
329-56-6
分子量：:
205.64
Beilstein:
3916100
EC號碼:
206-345-5
MDL號碼:
MFCD00064560
分類程式碼代碼:
12352209
PubChem物質ID:
57652452
NACRES:
NA.77

化驗

≥98.0% (sum of enantiomers, HPLC)

形狀

crystals

光學活性

[α]20/D −38.5±5°, c = 2% in H2O

mp

~150 °C (dec.)

儲存溫度

2-8°C

SMILES 字串

Cl[H].NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C8H11NO3.ClH/c9-4-8(12)5-1-2-6(10)7(11)3-5;/h1-3,8,10-12H,4,9H2;1H/t8-;/m0./s1

InChI 密鑰

FQTFHMSZCSUVEU-QRPNPIFTSA-N

基因資訊

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

生化／生理作用

Adrenal medullary stress hormone, mediator of the fight-or-flight response; and the primary neurotransmitter in the post-ganglionic sympathetic (adrenergic) nervous system.

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H300 + H310 + H330

危險分類

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

分析證明 (COA)

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Scientific reports, 9(1), 6151-6151 (2019-04-18)
Early diagnosis of Parkinson's disease (PD) remains a challenge to date. New evidence highlights the potential clinical value of circulating trace amines (TAs) in early-stage PD and their involvement in disease progression. A new ultra performance chromatography mass spectrometry (UPLC-MS/MS)
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The Laryngoscope, 124(5), E188-E193 (2013-10-12)
Noise generated by instruments, such as mastoid or craniotomy drills, may cause hearing damage by reducing the cochlear blood flow (CoBF). This study investigated whether dexmedetomidine can lessen noise-induced hearing loss (NIHL) in a guinea pig model. Animal study using
Wataru Inoue et al.
Nature neuroscience, 16(5), 605-612 (2013-04-09)
Exposure to a stressor sensitizes behavioral and hormonal responses to future stressors. Stress-associated release of noradrenaline enhances the capacity of central synapses to show plasticity (metaplasticity). We found noradrenaline-dependent metaplasticity at GABA synapses in the paraventricular nucleus of the hypothalamus
Sébastien Zanella et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(1), 36-50 (2014-01-02)
Neuronal networks are endogenously modulated by aminergic and peptidergic substances. These modulatory processes are critical for maintaining normal activity and adapting networks to changes in metabolic, behavioral, and environmental conditions. However, disturbances in neuromodulation have also been associated with pathologies.
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