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重要文件

481990

Sigma-Aldrich

尼日利亚菌素钠盐,吸水链霉菌

Disrupts the membrane potential and stimulates ATPase activity in mitochondria.

同義詞:

尼日利亚菌素钠盐,吸水链霉菌, 抗生素K178

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About This Item

經驗公式(希爾表示法):
C40H67O11 · Na
CAS號碼:
分子量::
746.94
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

化驗

≥98% (TLC)

形狀

lyophilized

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

溶解度

chloroform: soluble
ethanol: soluble
ethyl acetate: soluble

運輸包裝

ambient

儲存溫度

2-8°C

InChI

1S/C40H68O11.Na/c1-21-11-12-28(46-33(21)26(6)36(42)43)17-29-18-30(45-10)27(7)40(48-29)25(5)19-38(9,51-40)32-13-14-37(8,49-32)35-23(3)16-31(47-35)34-22(2)15-24(4)39(44,20-41)50-34;/h21-35,41,44H,11-20H2,1-10H3,(H,42,43);/q;+1/p-1/t21-,22-,23-,24+,25?,26?,27+,28+,29+,30+,31+,32?,33?,34-,35?,37?,38?,39-,40+;/m0./s1

InChI 密鑰

MOYOTUKECQMGHE-KKCUGXASSA-M

一般說明

一种可催化碱金属电子中性交换H+(反向运输)的单羧酸。按以下特异性排列进行单价阳离子跨膜运输:K+>Rb+>Cs+>>Na+。一种可通过促进离子跨膜扩散而杀死细菌的抗生素。破坏膜电位并刺激线粒体ATP酶活性。
破坏膜电位并刺激线粒体中的ATP酶活性。按以下特异性排列进行单价阳离子跨膜运输:K+>Rb+>Cs+>>Na+

生化/生理作用

产物不与ATP竞争。
可逆:否
细胞渗透性:否
首要靶标
破坏膜电位并刺激线粒体中的ATP酶活性。

警告

毒性:有毒(F)

重構

在重悬后分装并冻存。储备液可在-20°C稳定1个月。

其他說明

Moriyama, Y., et al. 1994.J. Biochem.115, 213.
Eytan, G.D., et al. 1990.J. Biol. Chem.265, 12949.
Alonso, M.A., and Carrasco, L. 1981.FEBS Lett.127, 112.
由于该运输中有害物质的性质,您的订单可能需要支付额外的运输费用。某些尺寸的产品可免除其他有害材料的运输费用。请与您当地的销售办事处联系,以获取有关这些费用的更多信息。

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Eye Irrit. 2

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3


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