475880
盐酸 ML-7-CAS 110448-33-4-Calbiochem
A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM).
同義詞:
ML-7, Hydrochloride, 1-(5-Iodonaphthalene-1-sulfonyl)homopiperazine, HCl
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About This Item
經驗公式（希爾表示法）:
C15H17IN2O2S · xHCl
CAS號碼:
分子量：:
416.28 (free base basis)
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77
推薦產品
品質等級
化驗
>98% (TLC)
形狀
solid
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
desiccated (hygroscopic)
protect from light
顏色
white
溶解度
50% ethanol: 4.5 mg/mL
DMSO: 4.5 mg/mL
運輸包裝
ambient
儲存溫度
2-8°C
InChI
1S/C15H17IN2O2S/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18/h1-2,4-7,17H,3,8-11H2
InChI 密鑰
GEHJIACZUFWBTK-UHFFFAOYSA-N
一般說明
A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). Inhibits protein kinase A (Ki = 21 µM) and protein kinase C (Ki = 42 µM) at much higher concentrations.
A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). Inhibits protein kinase A (Ki = 21 µM)and protein kinase C (Ki = 42 µM) at much higher concentrations.
生化／生理作用
Cell permeable: yes
Primary Target
Myosin light chain kinase (Mlck)
Myosin light chain kinase (Mlck)
Product competes with ATP.
Reversible: yes
Target Ki: 300 nM against myosin light chain kinase
警告
Toxicity: Standard Handling (A)
準備報告
Further dilute with aqueous buffer just prior to use.
重構
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
其他說明
Krarup, T., et al. 1998. Am. J. Physiol. 275, C239.
Saitoh, M., et al. 1987. J. Biol. Chem.262, 7796.
Saitoh, M., et al. 1987. J. Biol. Chem.262, 7796.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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