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Key Documents

36-002

Sigma-Aldrich

抗磷酸-SGK抗体

serum, Upstate®

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

phosphorylation (pSer422/pThr256)

基因資訊

human ... SGK1(6446)

特異性

可识别磷酸化SGK。

免疫原

对应于人SGK1的Ser255/Thr256周围氨基酸的肽

應用

不推荐与细胞裂解液同用。
抗磷酸化SGK抗体是针对磷酸化SGK的抗体,可用于WB。
研究子类别
PI3K、Akt & mTOR 信号传导
研究类别
信号传导

品質

用PDK1(目录号14-280)磷酸化未活化的SGK1(目录号14-332)后,通过免疫印迹检测到的磷酸SGK进行常规评估

標靶描述

48kda

外觀

含有30%甘油和0.035%叠氮化钠的未纯化全兔抗血清。
未纯化

儲存和穩定性

自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始样品瓶进行离心。

分析報告

对照
PDK活化的SGK样品

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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Phase II trial of temsirolimus in patients with metastatic breast cancer.
Gini F Fleming,Cynthia X Ma,Dezheng Huo,Husain Sattar,Maria Tretiakova,L Lin,Olwen M Hahn et al.
Breast Cancer Research and Treatment null
J Park et al.
The EMBO journal, 18(11), 3024-3033 (1999-06-05)
Serum and glucocorticoid-inducible kinase (SGK) is a novel member of the serine/threonine protein kinase family that is transcriptionally regulated. In this study, we have investigated the regulatory mechanisms that control SGK activity. We have established a peptide kinase assay for
Joseph R Shaw et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 22(1-4), 69-78 (2008-09-05)
Killifish are euryhaline teleosts that adapt to increased salinity by up regulating CFTR mediated Cl(-) secretion in the gill and opercular membrane. Although many studies have examined the mechanisms responsible for long term (days) adaptation to increased salinity, little is
T Kobayashi et al.
The Biochemical journal, 344 Pt 1, 189-197 (1999-11-05)
The catalytic domain of serum- and glucocorticoid-induced protein kinase (SGK) is 54% identical with protein kinase B (PKB) and, like PKB, is activated in vitro by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and in vivo in response to signals that activate phosphatidylinositol
George G Schweitzer et al.
Journal of applied physiology (Bethesda, Md. : 1985), 113(12), 1852-1861 (2012-09-01)
Prior exercise by rats can induce a sustained increase in muscle Akt substrate of 160 kDa (AS160) phosphorylation on Thr(642) (pAS160(Thr642)). Because phosphorylation of AS160 on both AS160(Thr642) and AS160(Ser588) is important for insulin-stimulated glucose transport (GT), we determined if

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