推薦產品
生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human
製造商／商標名
Upstate®
技術
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
phosphorylation (pSer422/pThr256)
基因資訊
human ... SGK1(6446)
特異性
可识别磷酸化SGK。
免疫原
对应于人SGK1的Ser255/Thr256周围氨基酸的肽
應用
不推荐与细胞裂解液同用。
抗磷酸化SGK抗体是针对磷酸化SGK的抗体，可用于WB。
研究子类别
PI3K、Akt & mTOR 信号传导
PI3K、Akt & mTOR 信号传导
研究类别
信号传导
信号传导
品質
用PDK1（目录号14-280）磷酸化未活化的SGK1（目录号14-332）后，通过免疫印迹检测到的磷酸SGK进行常规评估
標靶描述
48kda
外觀
含有30%甘油和0.035%叠氮化钠的未纯化全兔抗血清。
未纯化
儲存和穩定性
自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。
分析報告
对照
PDK活化的SGK样品
PDK活化的SGK样品
其他說明
浓度：请参考批次特异性浓缩物的检验报告。
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Phase II trial of temsirolimus in patients with metastatic breast cancer.
Gini F Fleming,Cynthia X Ma,Dezheng Huo,Husain Sattar,Maria Tretiakova,L Lin,Olwen M Hahn et al.
Breast Cancer Research and Treatment null
J Park et al.
The EMBO journal, 18(11), 3024-3033 (1999-06-05)
Serum and glucocorticoid-inducible kinase (SGK) is a novel member of the serine/threonine protein kinase family that is transcriptionally regulated. In this study, we have investigated the regulatory mechanisms that control SGK activity. We have established a peptide kinase assay for
Joseph R Shaw et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 22(1-4), 69-78 (2008-09-05)
Killifish are euryhaline teleosts that adapt to increased salinity by up regulating CFTR mediated Cl(-) secretion in the gill and opercular membrane. Although many studies have examined the mechanisms responsible for long term (days) adaptation to increased salinity, little is
T Kobayashi et al.
The Biochemical journal, 344 Pt 1, 189-197 (1999-11-05)
The catalytic domain of serum- and glucocorticoid-induced protein kinase (SGK) is 54% identical with protein kinase B (PKB) and, like PKB, is activated in vitro by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and in vivo in response to signals that activate phosphatidylinositol
George G Schweitzer et al.
Journal of applied physiology (Bethesda, Md. : 1985), 113(12), 1852-1861 (2012-09-01)
Prior exercise by rats can induce a sustained increase in muscle Akt substrate of 160 kDa (AS160) phosphorylation on Thr(642) (pAS160(Thr642)). Because phosphorylation of AS160 on both AS160(Thr642) and AS160(Ser588) is important for insulin-stimulated glucose transport (GT), we determined if
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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