345752

Ganglioside GD₃, Disialo, Diammonium Salt, Bovine Buttermilk

Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma.

• 同義詞: Ganglioside GD₃, Disialo, Diammonium Salt, Bovine Buttermilk, Neu5Acα2,8Neu5Acα2,3Galβ1,4Glcβ1,1 Ceramide, 2NH₄
• 經驗公式（希爾表示法）: C₇₀H₁₂₃N₃O₃₀ · 2NH₄
• 分子量：: 1522.80
• 分類程式碼代碼: 12352211
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (TLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: water: 1 mg/mL; chloroform/methanol (2:1): soluble
• 運輸包裝: ambient
• 儲存溫度: −20°C

描述

一般說明

Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma. Reported to disrupt mitochondrial transmembrane potential and induce apoptosis in tumor cells by a caspase-independent mechanism. Antibodies to GD₃ can induce partial remission of tumor growth in animals and in humans via enhancement of cytotoxic and proliferative responses of lymphocytes. M.W. 1577.0 (based on tricosanoyl - 23:0).

警告

Toxicity: Irritant (B)

其他說明

DeMaria, R., et al. 1997. Science 277, 1652.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable