317639

Dipeptidylpeptidase IV, His•Tag^®, Human, Recombinant, S. frugiperda

DPPIV is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes.

• 酶委員會編號: 3.4.14.5 (BRENDA, IUBMB)
• 分類程式碼代碼: 12352202
• NACRES: NA.54

屬性

• 品質等級: 100
• 化驗: ≥90% (SDS-PAGE)
• 形狀: liquid
• 比活性: ≥8 units/mg protein
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; avoid repeated freeze/thaw cycles
• 運輸包裝: wet ice
• 儲存溫度: −70°C

描述

一般說明

DPPIV is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes.

Note: 1 mU = 1 milliunit.

Recombinant, human DPP IV fused at the N-terminus to a His•Tag sequence and expressed in S. frugiperda insect cells. A serine exopeptidase dimer composed of two identical subunits of 110-130 kDa. DPPIV is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes. Note: 1 mU = 1 milliunit.

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

單位定義

One unit is defined as the amount of enzyme that will hydrolyze 1 µmole H-Gly-Pro-AMC per min at 37°C, pH 8.0.

外觀

In 20 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% NaN₃, pH 8.0.

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Pospisilik, JA, et al. 2003. Diabetes52, 741.
Dobers, J., et al. 2002. Protein Expr. Purif.25, 527.
Marguet, D., et al. 2000. Proc. Natl. Acad. Sci.97, 6874.
Misumi, Y., et al. 1992. Biochim. Biophys. Acta1131, 333.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: does not flash
• 閃點（°C）: does not flash