208922-M

CaMKII Inhibitor, CK59

The CaMKII Inhibitor, CK59, also referenced under CAS 140651-18-9, controls the biological activity of CaMKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 同義詞: CaMKII Inhibitor, CK59, 2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
• 經驗公式（希爾表示法）: C₂₁H₃₇N₇O₃
• CAS號碼: 140651-18-9
• 分子量：: 435.56
• MDL號碼: MFCD09262258
• 分類程式碼代碼: 12352200

屬性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: semisolid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: yellow
• 溶解度: DMSO: 10 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: [nH]1nc(c(c1N)N=Nc2ccc(cc2)O)N
• InChI: 1S/C9H10N6O/c10-8-7(9(11)15-14-8)13-12-5-1-3-6(16)4-2-5/h1-4,16H,(H5,10,11,14,15)
• InChI 密鑰: AYZRKFOEZQBUEA-UHFFFAOYSA-N

描述

一般說明

A cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC₅₀<10 µM) and inhibits insulin-stimulated glucose uptake (IC₅₀ ≤5 µM) and GLUT4 membrane translocation (IC₅₀ = 100 µM) in 3T3-L1 adipocytes.

A cell-permeable Olomoucine analog that acts as a CaMKII inhibitor (IC₅₀<10 M) and inhibits insulin-stimulated glucose uptake (IC₅₀ ≤5 M) and GLUT4 membrane translocation (IC₅₀ = 100 M) in 3T3-L1 adipocytes.

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他說明

Konstantopoulos, N., et al. 2007. Endocrinology, 148, 374.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable