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Merck
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Key Documents

14-455

Sigma-Aldrich

Rap1 Assay Reagent (Ral GDS-RBD, agarose), 650 µg

Reagent (Ral GDS-RBD, agarose). A GST-tagged fusion protein, corresponding to amino acids 788-884 of human Ral GDS-Rap binding domain (RBD), for use in Affinity Binding Assays.

同義詞:

Ral GDS-RBD Assay Reagent, Rap1 Detection Reagent

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About This Item

分類程式碼代碼:
12352204
eCl@ss:
32160405
NACRES:
NA.41

生物源

human

品質等級

形狀

liquid

製造商/商標名

Upstate®

技術

affinity binding assay: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

基因資訊

human ... TERF2IP(54386)

一般說明

A GST-tagged fusion protein, corresponding to amino acids 788-884 of human Ral GDS-Rap binding domain (RBD)
Product Source: expressed in E. coli

品質

routinely evaluated by immunoblot analysis

儲存和穩定性

6 months at -20C

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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Amlodipine potentiates metalloproteinase activity and accelerates elastin degradation in a model of aneurysmal disease.
J R Boyle,I M Loftus,S Goodall,M Crowther,P R Bell,M M Thompson
European Journal of Vascular and Endovascular Surgery null
Measurement of GTP-bound Ras-like GTPases by activation-specific probes.
M van Triest et al.
Methods in enzymology, 333, 343-348 (2001-06-13)
B Franke et al.
The EMBO journal, 16(2), 252-259 (1997-01-15)
Rap1 is a small, Ras-like GTPase whose function and regulation are still largely unknown. We have developed a novel assay to monitor the active, GTP-bound form of Rap1 based on the differential affinity of Rap1GTP and Rap1GDP for the Rap
J F Rebhun et al.
The Journal of biological chemistry, 275(45), 34901-34908 (2000-08-10)
Although the Ras subfamily of GTPases consists of approximately 20 members, only a limited number of guanine nucleotide exchange factors (GEFs) that couple extracellular stimuli to Ras protein activation have been identified. Furthermore, no novel downstream effectors have been identified
Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
Herrmann, C, et al
The Journal of Biological Chemistry, 271, 6794-6800 (1996)

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