14-1067

Human Recombinant MeCP2 (methyl-CpG-binding protein 2)

Human recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells & purified by Fast Protein Liquid Chromatography (FPLC) & demonstrated to bind methylated DNA

• 分類程式碼代碼: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

屬性

• 重組細胞: expressed in Sf9 cells
• 品質等級: 100
• 化驗: >95% (SDS-PAGE)
• 分子量: M_w 50.2 kDa (including histidine tag)
• 濃度: 0.5 μg/μL
• 運輸包裝: dry ice

描述

一般說明

Human recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells and purified by Fast Protein Liquid Chromatography (FPLC).

MeCP2 (methyl-CpG-binding protein 2) binds methylated CpG sequences in double-stranded DNA resulting in the suppression of transcription. This protein is likely to be involved in the repression of multiple genes. Consistent with this role, mutations of MeCP2 are linked to Rett syndrome, a progressive neurological disorder that is one of the most common causes of mental retardation in females.

應用

Research Category
Epigenetics & Nuclear Function

外觀

In a buffer containing 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.

儲存和穩定性

Stable at -80ºC for 6 months from date of receipt.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable