1.37172

聚山梨酯20

high purity, EMPROVE^® EXPERT, Ph. Eur., ChP, JPE, NF

• 同義詞: Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate, Polysorbate 20
• CAS號碼: 9005-64-5
• MDL號碼: MFCD00165986
• 分類程式碼代碼: 12161900
• 酶委員會索引編號: 500-018-3

屬性

• 生物源: synthetic
• 品質等級: 500
• 等級: GDP; GMP; Halal; Kosher
• agency: ChP; JPE; NF; Ph. Eur.
• 描述: GMO free; low in endotoxins
• 產品線: EMPROVE^® EXPERT
• 形狀: liquid
• 效力: 38900 mg/kg LD₅₀, oral
• 分子量: 1228 g/mol
• pH值: 6-8 (20 °C, 50 g/L, H2O)
• bp: >100 °C
• mp: 98.9 °C
• 密度: 1.1 g/cm³ at 25 °C
• 應用: liquid formulation; parenterals; pharmaceutical
• 異物活動: Aflatoxin free
• 儲存溫度: 15-25°C
• InChI: 1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
• InChI 密鑰: HMFKFHLTUCJZJO-UHFFFAOYSA-N

描述

一般說明

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Polysorbate 20 is used to stabilize biomolecule formulations and as solubilizer, emulsifier and wetting agent in small molecule formulation.


Polysorbates are known to degrade via autoxidation and hydrolysis. Degradation products can have a negative impact on the stability of the protein as well as the small molecule API. To reduce this risk, the polysorbate high-purity grade contains a low amount of impurities, especially peroxides.


Intended for high-risk applications, this Emprove^® Expert grade contains bioburden and endotoxin limits.

包裝

1.371720100 / 100ml / glass bottle
1.371721000 / 1l / glass bottle

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 527.0 °F - Pensky-Martens closed cup
• 閃點（°C）: 275 °C - Pensky-Martens closed cup