1.37037

氯化胍

EMPROVE^® EXPERT, NF

• 同義詞: 盐酸胍 盐酸盐, 亚氨基脲 盐酸盐, 亚氨脲 盐酸盐, 盐酸胍
• 線性公式: NH₂C(=NH)NH₂ · HCl
• CAS號碼: 50-01-1
• 分子量：: 95.53
• Beilstein: 3591990
• MDL號碼: MFCD00013026
• 分類程式碼代碼: 12352107
• 酶委員會索引編號: 200-002-3

屬性

• agency: NF
• 品質等級: 500
• 產品線: EMPROVE^® EXPERT
• 效力: 655.3-907.1 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rabbit)
• 特點: RNase and DNase free
• pH值: 4.5-5.5 (20 °C, 100 g/L in H₂O)
• mp: 180-185 °C (lit.); 188 °C
• 溶解度: 2150 g/L
• 密度: 1.3 g/cm³ (lit.)
• 體積密度: 550‑620 kg/m³
• 儲存溫度: 15-25°C
• SMILES 字串: Cl[H].NC(N)=N
• InChI: 1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
• InChI 密鑰: PJJJBBJSCAKJQF-UHFFFAOYSA-N

描述

一般說明

Finding the right chemical that matches your pharma and biopharma manufacturing needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for pharma and biopharma manufacturing withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Our SAFC^® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

應用

强效离液剂，用于蛋白质的变性以及后续复性。该强效变性剂可溶解不溶性或变性的蛋白质，如包涵体。可用作使蛋白质或酶复性为活性形式的第一步骤。可能还需要脲和二硫苏糖醇 (DTT)。

其他說明

Due to its low microbial and endotoxin limits, Guanidinium chloride Emprove^® Expert is suitable for biopharma manufacturing needs.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302 + H332 - H315 - H319
• 防範說明: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable