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Merck
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Key Documents

12-242

Sigma-Aldrich

Glycogen Synthase Peptide-2

Ala21, negative control for GSK-3β

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About This Item

分類程式碼代碼:
12352204
eCl@ss:
32160405
NACRES:
NA.42

product name

Glycogen Synthase Peptide-2 (Ala21), Glycogen Synthase Peptide-2 (Ala21) primarily used in Kinase Assays.

品質等級

製造商/商標名

Upstate®

技術

activity assay: suitable (kinase)

UniProt登錄號

運輸包裝

wet ice

品質

Routinely evaluated for use as a negative control for assay of GSK-3β (Catalog # 14-306) activity in a phosphorylation assay. Not to be used as a substrate for GSK3.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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S R Kimball et al.
The Journal of biological chemistry, 273(47), 30945-30953 (1998-11-13)
The present study was designed to investigate the mechanism through which leucine and histidine regulate translation initiation in L6 myoblasts. The results show that both amino acids stimulate initiation and coordinately regulate the activity of eukaryotic initiation factor eIF2B. The
Regulation and functions of the glycogen synthase kinase-3 subfamily.
Woodgett, J R
Seminars in cancer biology, 5, 269-275 (1994)
M P Coghlan et al.
Chemistry & biology, 7(10), 793-803 (2000-10-18)
Glycogen synthase kinase-3 (GSK-3) is a serine/threonine protein kinase, the activity of which is inhibited by a variety of extracellular stimuli including insulin, growth factors, cell specification factors and cell adhesion. Consequently, inhibition of GSK-3 activity has been proposed to

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