SCP0063

Calpastatin Peptide

≥95% (HPLC), Ac 184-210

• 經驗公式（希爾表示法）: C₁₄₂H₂₃₀N₃₆O₄₄S₁
• 分子量：: 3177.63
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• product name: Calpastatin Peptide Ac 184-210, ≥95% (HPLC)
• 化驗: ≥95% (HPLC)
• 形狀: lyophilized
• 成份: Peptide Content, ≥75%
• 儲存條件: protect from light
• 儲存溫度: −20°C

描述

Amino Acid Sequence

Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH2

應用

Calpastatin Peptide Ac 184-210 has been used as the endogenous calpain inhibitor to study its effects on myristoylated alanine-rich C kinase substrate (MARCKS) cleavage in mouse kidney cells. It has also been used as a calpain inhibitor to examine its effects on the formation of DNA-platinum adducts by cisplatin (CDDP) in neuronal cells.

生化／生理作用

Calpastatin, a component of the calpain/calpastatin system, is a calpain (calcium-dependent cysteine protease) inhibitor. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation.

Calpastatin, located in the cytosol, is involved in selective protein cleavage in response to calcium signaling.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable