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Merck
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重要文件

12-219

Sigma-Aldrich

Threonine Phosphopeptide

lyophilized powder, K-R-pT-I-R-R

同義詞:

Phosphopeptide K-R, Phosphopeptide K-R-pT-I-R-R, Threonine Phosphopeptide

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About This Item

分類程式碼代碼:
12352204
eCl@ss:
32160405
NACRES:
NA.41

產品名稱

苏氨酸磷酸肽(K-R-pT-I-R-R),

製造商/商標名

Upstate®

品質等級

技術

activity assay: suitable (kinase)

運輸包裝

wet ice

生化/生理作用

蛋白质靶标:PP2A

品質

通过使用PP2A免疫沉淀磷酸酶测定试剂盒(17-313)将该磷酸肽用作PP2A(14-111)的底物进行常规评估。 也可以使用Ser/Thr磷酸酶测定试剂盒1(17-127)进行测试。

外觀

冻干粉末

儲存和穩定性

冻干:在4°C下可稳定保存2年。再水化:在-20°C下可稳定保存1年。

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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P Agostinis et al.
European journal of biochemistry, 205(1), 241-248 (1992-04-01)
p34cdc2 kinase, a critical regulator of the cell cycle, has been shown to recognize the consensus sequence S/TP in proteins such as histone H1, the retinoblastoma gene product RB and the carboxyl-terminal domain of eukaryotic RNA polymerase II. Using phosphorylated
A Donella-Deana et al.
Biochimica et biophysica acta, 1094(1), 130-133 (1991-08-13)
The four main classes of protein phosphatases (PP-1, 2A, 2B and 2C), although differing in their ability to dephosphorylate phosphopeptide substrates, invariably display a marked preference toward phosphothreonyl peptides over their phosphoseryl counterparts. Conversely, all the acidic and alkaline phosphatases
Phosphorylated synthetic peptides as tools for studying protein phosphatases.
L A Pinna et al.
Biochimica et biophysica acta, 1222(3), 415-431 (1994-07-21)
M F Santoro et al.
The Journal of biological chemistry, 273(21), 13119-13128 (1998-05-28)
Although the available evidence suggests that whereas the caspase family plays a major role in apoptosis, they are not the sole stimulators of death. A random yeast two-hybrid screen of a lymphocyte cDNA library (using caspase-3 as the bait) found
K W Harder et al.
The Biochemical journal, 298 ( Pt 2), 395-401 (1994-03-01)
The intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) (44 kDa) was expressed in bacteria, purified using epitope 'tagging' immunoaffinity chromatography, and characterized with respect to kinetic profile, substrate specificity and potential modulators of enzyme activity. A chromogenic

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