119135

Adenosine A1 Receptor Agonist I, CPA

• 同義詞: Adenosine A1 Receptor Agonist I, CPA
• 經驗公式（希爾表示法）: C₁₅H₂₁N₅O₄
• CAS號碼: 41552-82-3
• 分子量：: 335.36
• MDL號碼: MFCD00036845
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 化驗: ≥99% (HPLC)
• 品質等級: 100
• 形狀: solid
• 效力: 0.8 nM K_i
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: white
• 溶解度: 1 M HCl: 100 mM; DMSO: 100 mM; ethanol: 25 mM
• 運輸包裝: ambient
• 儲存溫度: 2-8°C
• InChI: 1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15?/m1/s1
• InChI 密鑰: SQMWSBKSHWARHU-FJFSNTMWSA-N

描述

一般說明

A potent and selective agonist of adenosine A1 receptor (A1R) (K_i = 2.3 nM, 790 nM, 18.6 µM, 43nM for human A1, A2A, A2B, and A3, respectively).

生化／生理作用

Primary Target
A1

Reversible: yes

警告

Toxicity: Standard Handling (A)

準備報告

slight warming is required for complete solubilization in ethanol

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Migita, H., et al. 2008. J Neurosci Res.86, 2820.
Burgdorf, C. et al. 2005. J Cardiovasc Pharmacol.45, 1.
Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362, 382.
Mironov, S., et al. 1990. J Neurophysiol.81, 1.
Monopoli, A., et al. 1994. Arzneimittelforschung.44, 1305.
Concas, A., et al. 1993. J Pharmacol Exp Ther.267, 844.
Lohse, M. J., et al. 1988. Nauryn Schmiedebergs Arch Pharmacol.337, 687.
Coffin, V. L., et al. 1987. J Pharmacol Exp Ther.241, 76.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable