1.02307

α-Chymotrypsin from bovine pancreas

cryst. lyophilized 350 U/mg for biochemistry

• 分類程式碼代碼: 12352204
• NACRES: NA.21

屬性

• 形狀: solid
• 效力: >4000 mg/kg LD₅₀, oral (rat)
• pH值: 3-5 (10 g/L in H₂O)

描述

一般說明

α-Chymotrypsin (CT) is a member of the S1 family. It comprises a catalytic triad system including aspartate, histidine, and serine. It is produced by chymotrypsinogen in the pancreas and then secreted into the digestive tract.

應用

α-Chymotrypsin has been used to study its adsorption characteristics on solid/liquid interfaces under varying adsorption conditions.

生化／生理作用

α-Chymotrypsin (CT) closely denotes a group of digestive enzymes (trypsin, elastase) that hydrolyzes polypeptide chains. The catalytic triad system works together to regulate the nucleophilicity of the serine residue in catalysis. CT shows a capability to catalyze nonconventional synthetic reactions in water-miscible organic media. Additionally, it is also used as a tool in comparative studies of water-miscible and water-immiscible solvents.

特點和優勢

• Easily obtainable due to small size
• Relatively stable

分析報告

Appearance (description):lyophilisate
Appearance (colour):slightly yellowish
Activity (ATEE, pH 8.0, 25 °C):≥ 350 U/mg
Spec. activity (calc. on protein):ca. 400

安全資訊

• 象形圖: GHS07,GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H302 - H315 - H319 - H334 - H335 - H400
• 防範說明: P261 - P273 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1