1.00590

甘氨酸

crystalline, EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP

• 同義詞: 甘氨酸, 氨基乙酸
• 線性公式: NH₂CH₂COOH
• CAS號碼: 56-40-6
• 分子量：: 75.07
• Beilstein: 635782
• MDL號碼: MFCD00008131
• 分類程式碼代碼: 12352121
• 酶委員會索引編號: 200-272-2

屬性

• agency: BP; ChP; JP; Ph. Eur.; USP
• 品質等級: 500
• 蒸汽壓力: 0.0000171 Pa ( 25 °C)
• 描述: EMPROVE^® EXPERT Ph Eur,BP,JP,USP
• 產品線: EMPROVE^® EXPERT
• 化驗: 98.5-101.0% (calculated on dried substance, perchloric acid titration)
• 形狀: crystalline; solid
• 技術: inhibition assay: suitable
• pH值: 5.9-6.4 (20 °C, 50 g/L in H₂O)
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• 溶解度: soluble 250 g/L
• 密度: 1.161 g/cm³ at 20 °C
• 應用: liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical
• 儲存溫度: 2-30°C
• SMILES 字串: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI 密鑰: DHMQDGOQFOQNFH-UHFFFAOYSA-N

描述

一般說明

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Glycine is an amino acid which is used widely in the biopharma industry as stabilizer, tonicity modifier, buffer and precipitating agent. It is also used as an emollient, emulsifying agent and solubilizer in solid and semi-solid formulations.
Due to its low microbial and endotoxin limits, Glycine cryst. Emprove^® Expert is especially suitable for high-risk applications.

生化／生理作用

脊髓中的抑制性神经递质，NMDA受体的变构调节器。

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

The substance 1.00590 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable