09-893

Anti-BAF (BANF1) Antibody

serum, from rabbit

• 同義詞: 53 kDa BRG1-associated factor A, Actin-related protein Baf53a, BAF complex 53 kDa subunit, BRG1-associated factor, INO80 complex subunit K, actin-like 6A, actin-related protein 4, hArpN beta
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: serum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: rat, mouse, human
• 技術: western blot: suitable
• NCBI登錄號: NP_003851
• UniProt登錄號: O96019
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... BANF1(8815)

描述

一般說明

Barrier-to-auto integration factor (BAF or BANF1) plays fundamental roles in nuclear assembly, chromatin organization, gene expression and development. BAF may potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. BAF contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. BAF is exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. BAF is found in both the nucleus and cytoplasm and is significantly enriched at the nuclear inner membrane, diffused throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase.

特異性

This antibody recognizes BAF (BANF1).

免疫原

KLH-conjugated linear peptide corresponding to human BAF (BANF1).

應用

Use Anti-BAF (BANF1) Antibody (Rabbit Polyclonal Antibody) validated in WB to detect BAF (BANF1) also known as 53 kDa BRG1-associated factor A.

Western Blot Analysis: A 1:1,000 dilution from a previous lot detected BAF in C2C12, Hek293, HeLa, HepG2, Huvec, Jurkat, L6, NIH/3T3, PC12, PC3, and RAW264.7 cell lysates.

品質

Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected BAF in 10 µg of HeLa cell lysate.

標靶描述

~10 kDa

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1