推薦產品
生物源
rabbit
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human, rat
製造商／商標名
Upstate®
技術
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
phosphorylation (pThr172)
基因資訊
human ... PRKAA1(5562)
特異性
可识别磷酸化AMPKα。
免疫原
KLH偶联的合成肽，对应于人AMP活化蛋白激酶α2（AMPKα2）的磷酸化Thr172周围的氨基酸。
應用
抗磷酸化AMPK α（Tyr342）抗体是针对磷酸化AMPKα（Tyr342）的抗体，可用于WB。
品質
已通过免疫印迹对过夜饥饿的HEK293 细胞和部分纯化的大鼠肝脏AMPK的RIPA裂解液进行了常规评估
標靶描述
Mr 63 kDa
外觀
形式：纯化
分析報告
对照
血清饥饿HEK293 细胞
血清饥饿HEK293 细胞
其他說明
浓度：请参考批次特异性浓缩物的检验报告。
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
J F P Wojtaszewski et al.
Biochemical Society transactions, 31(Pt 6), 1290-1294 (2003-12-04)
The AMPK (5'AMP-activated protein kinase) is becoming recognized as a critical regulator of energy metabolism. However, many of these effects in muscle metabolism have been ascribed to AMPK based on the use of the unspecific activator AICAR (5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside). Using mouse
Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis.
Rutter, Guy A, et al.
The Biochemical Journal, 375, 1-16 (2003)
Mathias Fasshauer et al.
Biochimie, 86(11), 779-784 (2004-12-14)
Several adipocyte-secreted factors have been demonstrated to potentially link obesity, insulin resistance, and cardiovascular disease. Among those, adiponectin is an insulin-sensitizing and anti-inflammatory adipokine, concentrations of which are decreased in obesity-associated metabolic and vascular disorders. Recently, two adiponectin receptors (AdipoR)
Tue L Nielsen et al.
Molecular genetics and metabolism, 123(1), 21-27 (2017-11-28)
McArdle disease (glycogen storage disease type V) is an inborn error of skeletal muscle metabolism, which affects glycogen phosphorylase (myophosphorylase) activity leading to an inability to break down glycogen. Patients with McArdle disease are exercise intolerant, as muscle glycogen-derived glucose
Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.
Martin, JS; Beck, DT; Aranda, JM; Braith, RW
Journal of Applied Physiology (1985)
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