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Key Documents

07-140

Sigma-Aldrich

Anti-STAT2 Antibody

Upstate®, from rabbit

同義詞:

Anti-IMD44, Anti-ISGF-3, Anti-P113, Anti-PTORCH3, Anti-STAT113

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

mouse

製造商/商標名

Upstate®

技術

electrophoretic mobility shift assay: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... STAT2(6773)

特異性

STAT2

免疫原

GST-fusion protein corresponding to residues 672-925 of murine STAT2

應用

Anti-STAT2 Antibody is a Rabbit Polyclonal Antibody for detection of STAT2 also known as Signal Transducer & Activator of Transcription 2 & has been tested in EMSA, IP, WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

品質

routinely evaluated by immunoblot on

標靶描述

130kDa

外觀

Affinity Chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

儲存和穩定性

2 years at -20°C

分析報告

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene.
Zhu Guo, Sanjay Garg, Karen M Hill, Lakshmi Jayashankar, Myesha R Mooney, Mary Hoelscher et al.
Journal of immunology (Baltimore, Md. : 1950) (1950)
Connie C Qiu et al.
Oncoimmunology, 10(1), 1860477-1860477 (2021-01-19)
STAT2 is a central component of the ISGF3 transcriptional complex downstream of type I interferon (IFN-I) signaling. The significance of in vivo IFN-I/STAT1 signals in cDCs is well-established in the generation of antitumor cytotoxic T cell (CTL) responses. However, the role
Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.
Zurney, J; Kobayashi, T; Holm, GH; Dermody, TS; Sherry, B
Journal of virology null
Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.
Lagor, WR; Fields, DW; Bauer, RC; Crawford, A; Abt, MC; Artis, D; Wherry, EJ; Rader, DJ
Atherosclerosis null
M Matsumoto et al.
Biological chemistry, 380(6), 699-703 (1999-08-03)
The interferon-stimulated gene factor 3 (ISGF3) transcription factor has been extensively studied in the context of the type I interferon (IFN-alpha/beta)-mediated antiviral response; it consists of the major DNA-binding component p48, and the signal transducers and activators of transcription (Stat)1

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