推薦產品
生物源
rabbit
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
monoclonal
物種活性
human
製造商／商標名
Upstate®
技術
dot blot: suitable
inhibition assay: suitable (peptide)
multiplexing: suitable
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
dimethylation (Arg2)
基因資訊
human ... H3C1(8350)
一般說明
组蛋白H3是参与真核细胞染色质结构的五种主要组蛋白之一。H3具有一个主要的球状结构域和一个长N末端的尾巴，其与核糖体核小体′串珠′结构体的结构有关。
组蛋白H3的N末端尾部从球状核小体核心突起，其可能发生几种不同类型的表观遗传修饰，从而影响细胞过程。这些修饰包括甲基或乙酰基与赖氨酸和精氨酸的共价连接，以及丝氨酸或苏氨酸的磷酸化。
组蛋白H3的N末端尾部从球状核小体核心突起，其可能发生几种不同类型的表观遗传修饰，从而影响细胞过程。这些修饰包括甲基或乙酰基与赖氨酸和精氨酸的共价连接，以及丝氨酸或苏氨酸的磷酸化。
免疫原
一种含有序列AdimRTKQ的肽，对应于人组蛋白H3的二甲基-精氨酸2
應用
使用在DB、WB、PIA、Mplex中验证的抗二甲基组蛋白H3（Arg2）抗体（兔单克隆抗体）检测二甲基组蛋白H3（Arg2），也称为H3R2me2、组蛋白H3（二甲基R2）。
品質
对HeLa细胞的酸提取蛋白进行了常规评估
標靶描述
17kDa
外觀
形式：纯化
分析報告
对照
HeLa细胞的酸提取物
HeLa细胞的酸提取物
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Zichuan Liu et al.
Developmental biology, 368(2), 304-311 (2012-06-05)
Several research groups have suggested that the embryonic-abembryonic (Em-Ab) axis in the mouse can be predicted by the first cleavage plane of the early embryo. Currently, it is not known whether this early patterning occurs in cloned embryos produced by
Lessly P Sepulveda-Rincon et al.
Biology of reproduction, 95(6), 123-123 (2016-10-21)
The first lineage specification during mammalian embryo development can be visually distinguished at the blastocyst stage. Two cell lineages are observed on the embryonic-abembryonic axis of the blastocyst: the inner cell mass and the trophectoderm. The timing and mechanisms driving
Alessandra Di Lorenzo et al.
Nucleic acids research, 42(13), 8297-8309 (2014-06-19)
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that modifies histone tails. To help elucidate the biological function of PRMT6 in vivo, we generated transgenic mice that ubiquitously express PRMT6 fused to the hormone-binding portion of the estrogen receptor
Ayaz Ahmad et al.
PloS one, 6(8), e22664-e22664 (2011-08-20)
Post-translational methylation of arginine residues profoundly affects the structure and functions of protein and, hence, implicated in a myriad of essential cellular processes such as signal transduction, mRNA splicing and transcriptional regulation. Protein arginine methyltransferases (PRMTs), the enzymes catalyzing arginine
Analysis of histones in Xenopus laevis. I. A distinct index of enriched variants and modifications exists in each cell type and is remodeled during developmental transitions.
Shechter, D; Nicklay, JJ; Chitta, RK; Shabanowitz, J; Hunt, DF; Allis, CD
The Journal of Biological Chemistry null
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