推薦產品
品質等級
用途
kit sufficient for 96 wells
物種活性
human
製造商/商標名
SMC®
參數
25 μL sample volume (CSF)
50 μL sample volume (serum and plasma)
assay range
intra-assay cv: ≤10%
(n=3)
sensitivity: 0.87 pg/mL
standard curve range: 0.43-1500 pg/mL
linearity: 80-120%
recovery range: 80-120%
inter-assay cv: ≤11%
(n=3)
技術
single molecule counting: suitable
輸入
plasma (K2 EDTA)
cerebrospinal fluid (CSF)
serum
運輸包裝
wet ice
儲存溫度
2-8°C
一般說明
Neurofilament Light Chain (NF-L) is a low molecular weight member of a family of proteins involved in axonal development and function. NF-L accumulation is viewed as a telltale sign of axonal damage in the brain, and is a key marker in a wide range of neurodegenerative diseases, especially as a blood-based biomarker. We are proud to aid these efforts by offering the new SMC® Human NF-L High Sensitivity Immunoassay Kit. By coupling this assay with the powerful state-of-the-art SMCxPRO® detection system, researchers can accurately assess NF-L concentrations even in low abundance in human serum, plasma, and CSF samples, enabling studies that examine the relevance of this key analyte from health to disease.
Research Category:
Neuroscience
Neurological
Research Sub-Category:
Alzheimer′s Disease
Aging
Nervous System
Neurodegenerative Diseases
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neuroregenerative Medicine
Neuroscience
Research Category:
Neuroscience
Neurological
Research Sub-Category:
Alzheimer′s Disease
Aging
Nervous System
Neurodegenerative Diseases
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neuroregenerative Medicine
Neuroscience
特異性
This assay was tested for cross-reactivity with Neurofilament Medium Chain (NF-M), Neurofilament Heavy Chain (NF-H), phospho-Tau (T181), total Tau, and Glial Fibrillary Acidic Protein (GFAP). No cross-reactivity was detected with these analytes.
應用
Used for ultrasensitivite quantification of Human NF-L in human serum, plasma, and CSF.
特點和優勢
This SMC® kit features:
- Accurate and reproducible performance on the state-of-the-art SMCxPRO® ultrasensitive immunoassay system.
- Compatiblity with automated liquid handling
法律資訊
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
分析證明 (COA)
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