T-058

Tapentadol hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• 同義詞: Tapentadol hydrochloride solution
• 經驗公式（希爾表示法）: C₁₄H₂₃NO · HCl
• CAS號碼: 175591-09-0
• 分子量：: 257.80
• EC號碼: 200-659-6
• MDL號碼: MFCD00944992
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329826275
• NACRES: NA.24

屬性

• 等級: certified reference material
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 1.0 mg/mL in methanol (as free base)
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: Cl.CC[C@H]([C@@H](C)CN(C)C)c1cccc(O)c1
• InChI: 1S/C14H23NO.ClH/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12;/h6-9,11,14,16H,5,10H2,1-4H3;1H/t11-,14+;/m0./s1
• InChI 密鑰: ZELFLGGRLLOERW-YECZQDJWSA-N
• 基因資訊: human ... OPRM1(4988) , SLC6A2(6530)

描述

一般說明

Tapentadol represents the first new drug of the centrally-acting analgesic class approved in the US in more than 25 years. This Snap-N-Spike^® Reference Solution is suitable for many LC/MS or GC/MS applications, including forensic analysis, pharmaceutical analysis, pain prescription monitoring, and urine drug testing.

應用

• Extended-Release Formulation for Chronic Pain: Extended-release formulations of Tapentadol hydrochloride are developed to provide sustained pain relief for chronic conditions. This formulation reduces the frequency of dosing and enhances patient compliance, offering consistent pain management (Faria et al., 2017).
• Pharmaceutical Quality Control and Research: High-purity Tapentadol hydrochloride solutions are essential in pharmaceutical research and quality control. These solutions are used for the calibration of analytical instruments and ensuring the consistency and safety of pharmaceutical products (Fejos et al., 2014).
• Transdermal Delivery Systems: Innovative research has developed PEGylated ultra-deformable transferosomes for the transdermal delivery of Tapentadol, improving its bioavailability and analgesic activity. This method offers a non-invasive alternative for pain management (Deng et al., 2022).
• Innovative Pain Management Solutions: Research on new delivery methods, such as intranasal administration using chitosan nanoparticles, aims to enhance the therapeutic potential and patient compliance of Tapentadol hydrochloride solution for pain management (Javia & Thakkar, 2017).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes,Central nervous system
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup