Q-002

喹硫平-D_{8标准液 CRM} hemifumarate 溶液

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: (C₂₁D₈H₁₇N₃O₂S)₂ · C₄H₄O₄
• CAS號碼: 1435938-24-1
• 分子量：: 899.18
• EC號碼: 200-659-6
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 100 μg/mL in methanol (as free base)
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 形式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: OC(=O)\C=C\C(O)=O.[2H]C1([2H])N(CCOCCO)C([2H])([2H])C([2H])([2H])N(C2=Nc3ccccc3Sc4ccccc24)C1([2H])[2H].[2H]C5([2H])N(CCOCCO)C([2H])([2H])C([2H])([2H])N(C6=Nc7ccccc7Sc8ccccc68)C5([2H])[2H]
• InChI: 1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+/i2*9D2,10D2,11D2,12D2;
• InChI 密鑰: ZTHJULTYCAQOIJ-UXUYVNHUSA-N

描述

一般說明

喹硫平，商品名为思瑞康^®，是一种非典型抗精神病药物，用于治疗抑郁症、双相情感障碍和精神分裂症。该新内标物适用于多种GCM 和 LCMS 应用，包括患者水平定量、法医和法医毒理学分析、同位素稀释方法和校准品制备。

應用

• Measurement of quetiapine and four quetiapine metabolites in human plasma by LC-MS/MS.: This study presents a robust method for measuring quetiapine and its metabolites using LC-MS/MS, emphasizing the importance of stable isotope-labeled standards like Quetiapine-D8 hemifumarate. This solution is crucial for accurate metabolite analysis, antipsychotic drug research, and pharmacokinetic studies in pharmaceutical and biotechnological research (Fisher et al., 2012).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Seroquel is a registered trademark of Astrazeneca UK

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes,Central nervous system
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup