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Merck
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Q3638

Sigma-Aldrich

喹硫平 半富马酸盐

≥98% (HPLC)

同義詞:

2-[2-（4-二苯并[b，f] [1,4]硫氮杂-11-基-1-哌嗪基）乙氧基]乙醇半富马酸盐, 喹硫平富马酸盐

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About This Item

經驗公式（希爾表示法）:
C21H25N3O2S · 0.5C4H4O4
CAS號碼:
111974-72-2
分子量：:
441.54
MDL號碼:
MFCD03423782
分類程式碼代碼:
12352200
PubChem物質ID:
329823864
NACRES:
NA.77

品質等級

100

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

white to off-white

溶解度

DMSO: >10 mg/mL

起源

AstraZeneca

儲存溫度

2-8°C

SMILES 字串

OC(=O)\C=C\C(O)=O.OCCOCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OCCOCCN5CCN(CC5)C6=Nc7ccccc7Sc8ccccc68

InChI

1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChI 密鑰

ZTHJULTYCAQOIJ-WXXKFALUSA-N

基因資訊

human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)

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一般說明

喹硫平是一种二苯并硫氮杂卓衍生物，也称为舍罗库尔和氯马斯汀。

應用

喹硫平半富马酸盐已被用作β-抑制蛋白2 突变体T205M 募集的拮抗剂。

生化／生理作用

喹硫平促进少突胶质细胞的体外形成。它用于治疗抑郁症。
喹硫平半富马酸盐是一种非典型抗精神病药，一种联合血清素（5HT2）和多巴胺（D2）受体拮抗剂。

特點和優勢

《受体分类和信号转导》手册的多巴胺受体页有该化合物的介绍。想要浏览手册的其他页面， 请单击此处。
该化合物由AstraZeneca开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

象形圖

Exclamation markEnvironment
GHS07,GHS09

訊號詞

Warning

危險聲明

H302,H400

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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