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Key Documents

P-164

Supelco

Phosphatidylethanol 16:0/18:1-D5 (PEth 16:0/18:1-D5) solution

100 μg/mL in methanol ((as free phosphate)), certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

經驗公式(希爾表示法):
C39H69D5O8P · NH4
CAS號碼:
分子量::
725.04
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

品質等級

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

100 μg/mL in methanol ((as free phosphate))

格式

single component solution

儲存溫度

−70°C

一般說明

This stable-labeled internal standard is suitable for quantitation of PEth 16:0/18:1 in LC/MS or GC/MS applications. PEth 16:0/18:1, also known as phosphatidylethanol 16:0/18:1, is a sensitive and specific biomarker for alcohol use and abuse. Since the detection window of PEth 16:0/18:1 in blood is longer than that of ethyl glucuronide (EtG) or ethyl sulfate (EtS) in urine, measurement of blood PEth 16:0/18:1 level is routinely performed in clinical toxicology and forensic testing applications such as abstinence monitoring and workplace drug testing. PEth 16:0/18:1 has also been investigated as a biomarker to confirm prenatal alcohol exposure (PAE).

應用


  • PEth 16:0/18:1-D5 in clinical biomarker research: A study in the Journal of Chromatography B validated a liquid chromatography tandem mass spectrometry (LC-MS/MS) method for analyzing erythrocyte phosphatidylethanol, including deuterated standards like PEth 16:0/18:1-D5. This method highlights critical considerations for using PEth as a clinical biomarker, particularly in monitoring alcohol consumption. The use of deuterated PEth standard ensures precision in quantifying PEth levels, supporting its role in lipidomics and alcohol abuse biomarker detection (White et al., 2022).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

49.5 °F

閃點(°C)

9.7 °C


分析證明 (COA)

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