O-008

羟考酮-D_{6标准液 CRM} 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: C₁₈H₁₅NO₄D₆
• CAS號碼: 152477-91-3
• 分子量：: 321.40
• EC號碼: 200-659-6
• MDL號碼: MFCD00673304
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329818817
• NACRES: NA.24

屬性

• 等級: certified reference material
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 1.0 mg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 儲存溫度: 2-8°C
• SMILES 字串: [2H]C([2H])([2H])Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)C([2H])([2H])[2H]
• InChI: 1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1/i1D3,2D3
• InChI 密鑰: BRUQQQPBMZOVGD-UKHJWGAOSA-N

描述

一般說明

稳定标记的内标物，适用于通过 LC/MS 或 GC/MS 定量测定尿液、血清或血浆中的羟考酮水平，用于尿液药物检测、临床毒理学、法医学分析或同位素稀释法。羟考酮是一种半合成阿片类镇痛药，以许多商品名销售，包括奥施康定 ^® 和 Percocet ^®，用于治疗中度至重度疼痛。羟考酮还以“Roxies”、“Blues”和“Perks”等商品名非法销售。

應用

• Oxycodone-D₆ as an isotopic standard: Oxycodone-D₆ is employed extensively as a high-quality isotopic standard in analytical chemistry, particularly in mass spectrometry. This application is crucial for ensuring accuracy and precision in the quantification of oxycoDonein various biological matrices, enhancing drug monitoring and forensic analyses.


• Stable isotope-labeled oxycoDonefor pharmacokinetic studies: Researchers use Oxycodone-D₆ to investigate the pharmacokinetics of oxycodone, including its absorption, distribution, metabolism, and excretion. The use of this stable isotope-labeled compound allows for more precise tracking of drug metabolites, contributing significantly to the understanding of drug behavior in the human body.


• Oxycodone-D₆ in metabolite analysis: The deuterated form of oxycoDoneis critical in metabolite profiling studies. It serves as an internal standard that facilitates the identification and quantification of oxycoDonemetabolites, thereby aiding in the exploration of metabolic pathways and potential drug interactions.


• Use in analytical standard development for biochemistry research: Oxycodone-D₆ solution is integral to developing robust analytical methods for drug testing and research. Its stability and reliability make it a preferred choice for validating new analytical techniques in biochemistry labs.


• Investigation of opioid receptor binding assays: This compound is utilized in studies exploring opioid receptor interactions, aiding in the development of targeted therapies for pain management. Oxycodone-D₆ helps in understanding the binding efficiency and pharmacodynamics of opioids at the molecular level.

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

OxyContin is a registered trademark of Purdue Pharma L.P.

Percocet is a registered trademark of Endo Pharmaceuticals Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup