F-050

4-氟异丁酰芬太尼标准液 溶液

100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant^®

• 經驗公式（希爾表示法）: C₂₃H₂₉FN₂O
• CAS號碼: 244195-32-2
• 分子量：: 368.49
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 0.5 mL
• 製造商／商標名: Cerilliant^®
• drug control: estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 100 μg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: O=C(N(C1-;@C-;@C-;@N(-;@C-;@C-;@1)CCC2=CC=CC=C2)C3=;@C-;@C=;@C(F)-;@C=;@C-;@3)C(C)C

描述

一般說明

4-Fluoro-isobutyryl fentanyl, also known as 4-FIBF and p-FIBF, is a fentanyl analog and sold on the illicit market as designer drug. This certified Snap-N-Spike^® solution is suitable for use as starting material in calibrators and controls for 4-Fluoro-isobutyryl fentanyl LC/MS or GC/MS testing methods in clinical toxicology, urine drug testing, or forensic analysis applications. This certified solution standard is DEA-exempt, allowing laboratories to place orders without additional regulatory paperwork. For US customers, state specific regulatory requirements may apply.

應用

• Real-time forensic surveillance: The study conducted by King County Medical Examiner′s Office implemented in-house drug evidence testing for rapid surveillance of fatal overdoses, a method pertinent to evaluating 4-Fluoro-isobutyryl fentanyl in forensic settings, enhancing opioid detection protocols (Harruff et al., 2024).


• Cytochrome P450 enzyme expression analysis: Research on mRNA expression levels of CYP1A2, CYP3A4, and CYP3A5 provides a foundational approach to understanding individual metabolic variations which could influence the biochemical research and pharmacokinetic studies of synthetic opioid analogs such as 4-Fluoro-isobutyryl fentanyl (Makihara et al., 2024).


• Pain management in clinical settings: A case report on the use of continuous intravenous fentanyl for treating oral mucosal pain in Stevens-Johnson Syndrome illustrates the clinical implications of potent fentanyl derivatives and supports research into similar compounds like 4-Fluoro-isobutyryl fentanyl for therapeutic uses (Ito et al., 2024).


• Dependency reversal in pharmacological research: A study on the efficacy of lipophilic analogues of D-cysteine to prevent and reverse physical dependence to fentanyl in rats underscores the importance of ongoing research into opioid receptor agonists and the potential impact of analogues like 4-Fluoro-isobutyryl fentanyl on addiction treatment strategies (Bates et al., 2023).


• Advanced detection techniques: Development of carbon nanofiber-modified electrodes for the electrochemical determination of fentanyl showcases technological advancements that could be adapted for enhanced detection and analysis of fentanyl analogues, including 4-Fluoro-isobutyryl fentanyl, in various biological matrices (Marenco et al., 2024).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup