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Merck
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重要文件

C-128

Supelco

卡马西平-10,11-环氧化物-13C6 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

經驗公式(希爾表示法):
13C6C9H12N2O2
分子量::
258.22
EC號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

品質等級

形狀

liquid

特點

(Snap-N-Spike®)

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

100 μg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

形式

single component solution

儲存溫度

−20°C

一般說明

这种稳定标记的内标物适用于疼痛处方监测、临床毒理学、治疗药物监测或尿液药物测试等应用中卡马西平水平或同位素稀释分析法的GC/MS或LC/MS定量测定。卡马西平10,11-环氧化物是卡马西平的主要活性代谢产物,卡马西平是一种抗惊厥和稳定情绪的药物,主要用于癫痫和神经性疼痛的治疗。

應用

<ul>
<li><strong>Pharmacological Research in Neuropsychiatry:</strong> This compound is instrumental in studies examining cannabidiol and its derivatives for their potential to reduce hyperalgesia and allodynia in conditions like trigeminal neuralgia. Research focuses on the interaction with TRPV1 receptors, offering insights into new therapeutic approaches for pain management (Escobar-Espinal et al., 2024).</li>
<li><strong>Advances in Solid Phase Microextraction:</strong> Carbamazepine-10,11-epoxide-13C6 explores is used in covalent organic framework-based solid phase microextraction techniques. These advancements are particularly useful in sensitive screening and quantitative analysis of drugs and their metabolites in biological samples, enhancing the precision of toxicological studies. It is also used in the treatment of epilepsy and neuropathic pains. (Huang et al., 2022).</li>
</ul>

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


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