B-901

丁丙诺啡-D₄ 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: C₂₉H₃₇NO₄D₄
• CAS號碼: 136781-89-0
• 分子量：: 471.66
• EC號碼: 200-659-6
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• 濃度: 100 μg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 儲存溫度: 2-8°C
• SMILES 字串: [2H]C1([2H])CC1C([2H])([2H])N2CC[C@]34[C@H]5Oc6c(O)ccc(C[C@@H]2[C@]37CC[C@@]5(OC)[C@H](C7)[C@](C)(O)C(C)(C)C)c46
• InChI: 1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1/i6D2,16D2/t17?,20-,21-,24-,26+,27-,28+,29-
• InChI 密鑰: RMRJXGBAOAMLHD-UHGBJPCQSA-N

描述

一般說明

An internal standard suitable for buprenorphine testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, pain prescription monitoring, urine drug testing, or forensic analysis. Buprenorphine is a semi-synthetic opiate used in the treatment of moderate acute pain and opioid addiction. The drug is sold under numerous trade names such as Suboxone^®, Subutex^®, and Temgesic.

應用

• Determination of buprenorphine and norbuprenorphine in urine and hair by gas chromatography-mass spectrometry - This pivotal study utilizes Buprenorphine-D₄ as an internal standard to enhance the analytical accuracy of buprenorphine and its metabolite norbuprenorphine in biological samples, crucial for opioid pharmacokinetics study and drug monitoring (Vincent et al., 1999).


• HPLC-MS for the determination of sildenafil citrate (Viagra) in biological fluids. Application to the salivary excretion of sildenafil after oral intake - Although this study primarily focuses on sildenafil, the methodology involving high-performance liquid chromatography coupled with mass spectrometry (HPLC-MS) where Buprenorphine-D₄ can be utilized as an internal standard demonstrates its broader application potential in drug metabolism and pharmacokinetic research, especially in studies involving complex biological matrices (Tracqui et al., 2003).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Suboxone is a registered trademark of RB Pharmaceuticals Limited

Subutex is a registered trademark of RB Pharmaceuticals Limited

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes,Central nervous system
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup