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A-913

Supelco

7-氨基硝基安定 溶液

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

經驗公式(希爾表示法):
C15H13N3O
CAS號碼:
分子量::
251.28
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

1.0 mg/mL in acetonitrile

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

格式

single component solution

儲存溫度

2-8°C

SMILES 字串

O=C1NC2=CC=C(N)C=C2C(C3=CC=CC=C3)=NC1

InChI

1S/C15H13N3O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9,16H2,(H,18,19)

InChI 密鑰

OYOUQHVDCKOOAL-UHFFFAOYSA-N

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一般說明

7-Aminonitrazepam is a major urinary metabolite of nitrazepam, a benzodiazepine used to treat insomnia and sold under the trade names Mogadon and Alodorm. This certified solution standard is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug monitoring of nitrazepam use.

應用

<ul>
<li><strong>7-Aminonitrazepam in forensic toxicology:</strong> 7-Aminonitrazepam is used as an analytical reference in the evaluation of hyperlipidemic postmortem blood, demonstrating its importance in forensic settings for accurate drug profiling (Elenst&aring;l et al., 2023).</li>
</ul>

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

FlameExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

35.6 °F - closed cup

閃點(°C)

2 °C - closed cup


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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S Takeno et al.
Toxicology and applied pharmacology, 121(2), 233-238 (1993-08-01)
This study was designed to evaluate the developmental toxicity of nitrazepam (NZ) in Sprague-Dawley rats and ICR mice and to determine the metabolic factors which modulate susceptibility to the developmental effects of NZ. Rats were treated orally with a single
Yu Zhu et al.
Se pu = Chinese journal of chromatography, 20(5), 394-397 (2005-12-20)
A highly sensitive method has been developed for the analysis of 7-aminonitrazepam (7-ANIZ), the major metabolite of nitrazepam, in urine by trimethylsilyl derivatization-gas chromatography/mass spectrometry. Urine samples were extracted with ethyl ether-ethyl acetate (99:1, volume ratio). The extracts were derivatized
B J Hart et al.
Methods and findings in experimental and clinical pharmacology, 10(1), 21-26 (1988-01-01)
The stability of some selected benzodiazepines in saliva has been studied. The benzodiazepines nitrazepam and clonazepam were found to be unstable in saliva at room temperature and nitrazepam was converted into 7-aminonitrazepam. The conversion rate of nitrazepam was strongly dependent
J Feely et al.
Irish journal of medical science, 168(1), 8-9 (1999-03-31)
An alarming increase in the misuse/abuse of nitrobenzodiazepine derivatives, especially flunitrazepam, prompted us to establish reliable analytical protocols for their routine detection. Whilst the parent drugs are readily available from a number of commercial sources, it was found difficult to
Fumio Moriya et al.
Forensic science international, 131(2-3), 108-112 (2003-02-19)
We report a case of nitrazepam poisoning in which the distribution of nitrazepam and 7-aminonitrazepam was determined in body fluids and tissues. A 52-year-old woman was found dead in a shallow ditch (approximately 5 cm in depth), in the winter.

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