推薦產品
等級
certified reference material
品質等級
形狀
liquid
特點
SNAP-N-SPIKE®, SNAP-N-SHOOT®
包裝
ampule of 1 mL
製造商/商標名
Cerilliant®
濃度
1.0 mg/mL in methanol
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
clinical testing
格式
single component solution
儲存溫度
2-8°C
SMILES 字串
OCc1nnc2CN=C(c3ccccc3)c4cc(Cl)ccc4-n12
InChI
1S/C17H13ClN4O/c18-12-6-7-14-13(8-12)17(11-4-2-1-3-5-11)19-9-15-20-21-16(10-23)22(14)15/h1-8,23H,9-10H2
InChI 密鑰
ZURUZYHEEMDQBU-UHFFFAOYSA-N
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一般說明
A major urinary metabolite of the benzodiazepine alprazolam. Alprazolam, commonly sold under the trade name Xanax®, is a short-acting anxiolytic approved to treat panic and other anxiety disorders including generalized or social anxiety disorder. This certified Snap-N-Spike® solution standard is suitable for use in LC/MS or GC/MS applications such as forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring.
應用
- Application of chemometric approach for development and validation of high performance liquid chromatography method for estimation of ropinirole hydrochloride.: This study employs the LiChrospher® 100 RP-18 endcapped (5 µm) column for the estimation of ropinirole hydrochloride, showcasing its efficacy in the development of a robust HPLC method. The chemometric approach enhances method development and validation, demonstrating high precision and accuracy (Fatima et al., 2019).
- Rapid, highly sensitive method for the determination of morphine and its metabolites in body fluids by liquid chromatography-mass spectrometry.: Utilizing the LiChrospher® 100 RP-18 endcapped (5 µm) column, this study develops a highly sensitive LC-MS method for detecting morphine and its metabolites in body fluids, underscoring the column′s capability in bioanalytical applications (Schänzle et al., 1999).
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Xanax is a registered trademark of Pharmacia & Upjohn Company
相關產品
產品號碼
描述
訂價
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes,Central nervous system
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
49.5 °F - closed cup
閃點(°C)
9.7 °C - closed cup
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Journal of forensic and legal medicine, 14(6), 348-351 (2007-07-17)
Alprazolam is widely used as a short-acting antidepressant and anxiolytic agent and its effect appears at very low doses while ethanol is used as a social drug worldwide. Sometimes, toxic interactions occur following combined administration of these two drugs. In
Metabolism of alprazolam (a marker of CYP3A4) in hemodialysis patients with persistent inflammation.
European journal of clinical pharmacology, 68(5), 571-577 (2011-12-14)
To investigate the impact of persistent inflammation in hemodialysis (HD) patients on the pharmacokinetics of alprazolam, a cytochrome P450 (CYP) 3A4 substrate, and its metabolites and the role of HD in the impact of persistent inflammation in this clinical context.
Bioanalysis, 3(20), 2303-2310 (2011-10-21)
Conventional liquid-handling devices were employed, along with an improved punching device, to semi-automate dried blood spot (DBS) extraction of alprazolam, α-hydroxyalprazolam and midazolam from human whole blood. Liquid-handling devices were used to add internal standard to the DBS cards and
Journal of analytical toxicology, 17(7), 427-431 (1993-11-01)
Adinazolam is a triazolobenzodiazepine, currently under clinical investigation, that possesses antidepressant and anxiolytic activity. It has a short half-life (less than 3 h), and less than 2% of an oral dose is excreted unchanged. The major urinary metabolite is N-desmethyladinazolam
[Pharmacological studies on alprazolam, and its main metabolites, alpha-OH-alprazolam and HB compound (author's transl)].
Igaku kenkyu. Acta medica, 50(7), 495-507 (1980-10-01)
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