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重要文件

LM1701

Avanti

17:1 Lyso PA

Avanti Research - A Croda Brand

同義詞:

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt)

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About This Item

經驗公式(希爾表示法):
C20H42NO7P
CAS號碼:
分子量::
439.52
分類程式碼代碼:
51191904
NACRES:
NA.25

形狀

methanol solution

包裝

pkg of 1 × 1 mL (LM1701-1EA)

製造商/商標名

Avanti Research - A Croda Brand

濃度

~10 μg/mL (Refer to C of A for lot specific concentration. )

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[NH4+]

一般說明

Lysophosphatidic acid (Lyso PA) is a water-soluble lipid, localized to all cells and tissues in mammals.

應用

17:1 Lyso PA or 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt) has been used as an internal standard for unsaturated lysophosphatidic acid (LPA) ester and cyclic LPA ethers in reversed-phase ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS/MS).

生化/生理作用

Lysophosphatidic acid (Lyso PA) is considered as a biological modulator of various functions in the cell. It is a potent signaling molecule with growth-factor-like actions. Lyso PA regulates cell proliferation, survival, cytoskeletal modification and calcium influx. It is associated with smooth-muscle contraction and platelet aggregation. It is also known to regulate blood pressure. Lyso PA possess extensive biological actions and is involved in the progression of several human cancer.

包裝

2 mL Amber Glass Sealed Ampule (LM1701-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


分析證明 (COA)

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Gordon B Mills et al.
Nature reviews. Cancer, 3(8), 582-591 (2003-08-02)
The bioactive phospholipid lysophosphatidic acid (LPA) stimulates cell proliferation, migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA production, receptor expression and signalling probably contribute to cancer initiation, progression and metastasis. The recent identification of ecto-enzymes that

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