推薦產品
化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1x10 mg (900408P-10MG)
pkg of 1 × 1 mg (with stopper and crimp cap (900408P-1mg))
pkg of 1 × 5 mg (with stopper and crimp cap (900408P-5mg))
製造商／商標名
Avanti Research™ - A Croda Brand 900408P
脂質類型
click reagents
phospholipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
C#CCCCC1(N=N1)CCCCCCCCC(OC[C@@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O)=O
一般說明
The pacFA lipid attached to 2-oleoyl-sn-glycero-3-phosphocholine, contains a photoactivable diazirine ring with a clickable alkyne group.
生化／生理作用
1-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-2-oleoyl-sn-glycero-3-phosphocholine (pacFA-18:1 PC) may be used for global analysis of protein–lipid interactions in living cells. pacFA acts as a precursor for the biosynthesis of bifunctional lipids. Proteins in contact with the bifunctional lipids are then cross-linked by ultraviolet (UV) irradiation of the diazirine ring. Finally, click chemistry is used to label the alkyne with a reporter molecule.
包裝
2 mL Amber Serum Vial with Stopper and Crimp Cap (900408P-1mg)
2 mL Amber Serum Vial with Stopper and Crimp Cap (900408P-5mg)
5 mL Amber Glass Screw Cap Vial (900408P-10MG)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
閃點（°F）
No data available
閃點（°C）
No data available
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Mathias J Gerl et al.
PloS one, 11(4), e0153009-e0153009 (2016-04-23)
Cell membranes contain hundreds to thousands of individual lipid species that are of structural importance but also specifically interact with proteins. Due to their highly controlled synthesis and role in signaling events sphingolipids are an intensely studied class of lipids.
In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids.
Per Haberkant et al.
Angewandte Chemie (International ed. in English), 52(14), 4033-4038 (2013-03-02)
Per Haberkant et al.
Biochimica et biophysica acta, 1841(8), 1022-1030 (2014-01-21)
Understanding biological processes at the mechanistic level requires a systematic charting of the physical and functional links between all cellular components. While protein-protein and protein-nucleic acid networks have been subject to many global surveys, other critical cellular components such as
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