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重要文件

890895C

Avanti

18:1 TAP (DOTAP, MS Salt)

Avanti Research - A Croda Brand 890895C

同義詞:

1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt)

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About This Item

經驗公式(希爾表示法):
C43H83NO8S
CAS號碼:
分子量::
774.19
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

liquid

包裝

pkg of 1 × 2.5 mL (890895C-25mg)
pkg of 2 × 4 mL (890895C-200mg)

製造商/商標名

Avanti Research - A Croda Brand 890895C

濃度

10 mg/mL (890895C-25mg)
25 mg/mL (890895C-200mg)

脂質類型

cationic lipids
transfection

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.O=S([O-])(OC)=O

InChI

1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;

InChI 密鑰

RSMRWWHFJMENJH-LQDDAWAPSA-M

生化/生理作用

DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP. DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).

包裝

5 mL Clear Glass Sealed Ampule (890895C-200mg)
5 mL Clear Glass Sealed Ampule (890895C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

標靶器官

Liver,Kidney, Respiratory system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Efficient siRNA delivery by the cationic liposome DOTAP in human hematopoietic stem cells differentiating into dendritic cells
Martino S, et al.
BioMed Research International, 2009 (2009)
DOTAP (and other cationic lipids): chemistry, biophysics, and transfection
Simberg D, et al.
Critical Reviews in Therapeutic Drug Carrier Systems, 21(4) (2004)
DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes
Kim BK, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(10), 1996-2001 (2015)

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