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890860P

Avanti

14:0 TAP

Avanti Research - A Croda Brand 890860P, powder

同義詞:

1,2-dimyristoyl-3-trimethylammonium-propane (chloride salt)

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About This Item

經驗公式(希爾表示法):
C34H68NO4Cl
CAS號碼:
分子量::
590.36
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 200 mg (890860P-200mg)

製造商/商標名

Avanti Research - A Croda Brand 890860P

脂質類型

cationic lipids
transfection

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]

InChI

1S/C34H68NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-33(36)38-31-32(30-35(3,4)5)39-34(37)29-27-25-23-21-19-17-15-13-11-9-7-2;/h32H,6-31H2,1-5H3;1H/q+1;/p-1

InChI 密鑰

WOSYUIOSAOFINL-UHFFFAOYSA-M

一般說明

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.

應用

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:
  • the preparation of cationic liposomes
  • reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
  • composing lipid–styrene maleic acid (SMA) complexes
  • liposome preparation by double emulsion method

生化/生理作用

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

包裝

5 mL Amber Glass Screw Cap Vial (890860P-200mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Masafumi Tanaka et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183209-183209 (2020-02-01)
Styrene maleic acid copolymers (SMA) form discoidal lipid nanoparticles (lipid nanodisks) that mimic plasma high-density lipoproteins. We have previously prepared and characterized lipid nanodisks composed of SMA and the neutral phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). In the present study, we tested whether
Lipid-induced dynamics of photoreceptors monitored by time-resolved step-scan FTIR spectroscopy
Jawurek M, et al.
Chemical Physics, 512, 53-61 (2018)
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)
Nishu Kanwa et al.
Physical chemistry chemical physics : PCCP, 22(6), 3234-3244 (2020-01-30)
In the present contribution, we investigate the interactions of lipid bilayer membranes of different charges and different phase states with aliphatic amino acids of varying charge (aspartic acid, glutamic acid, arginine and lysine) and hydrophobicity (serine, leucine and valine) by

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