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Key Documents

890880P

Avanti

18:0 TAP

Avanti Polar Lipids 890880P, powder

同義詞:

1,2-硬脂酰-3-三甲基铵-丙烷(氯化物盐)

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About This Item

經驗公式(希爾表示法):
C42H84NO4Cl
CAS號碼:
分子量::
702.57
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 200 mg (890880P-200mg)
pkg of 1 × 25 mg (890880P-25mg)

製造商/商標名

Avanti Polar Lipids 890880P

脂質類型

cationic lipids
transfection

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Cl-]

應用

1,2-硬脂酰-3-三甲基铵-丙烷(18:0 TAP)可用于:
  • 通过薄膜水合技术制备三负载胆汁糖体(Tri-BLs)
  • 配制脂质纳米颗粒(LNP),以测试其将 mRNA 包装成 LNP 的效率
  • 制造单层空脂质体
  • 制备脂质复合物

生化/生理作用

1,2-硬脂酰-3-三甲基铵-丙烷(18:0 TAP)是一种用于 DNA 转染的阳离子脂质。

包裝

5 mL棕色玻璃螺旋盖小瓶(890880P-200mg)
5 mL棕色玻璃螺旋盖小瓶(890880P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


分析證明 (COA)

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A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)
Yuki Takechi-Haraya et al.
Langmuir : the ACS journal of surfaces and colloids, 34(26), 7805-7812 (2018-06-06)
It has recently been recognized that the mechanical properties of lipid nanoparticles play an important role during in vitro and in vivo behaviors such as cellular uptake, blood circulation, and biodistribution. However, there have been no quantitative investigations of the

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