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重要文件

890717O

Avanti

14:1 EPC (Tf Salt)

Avanti Research - A Croda Brand 890717O

同義詞:

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (Tf salt)

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About This Item

經驗公式(希爾表示法):
C39H73F3NO11PS
CAS號碼:
分子量::
852.03
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

liquid

包裝

pkg of 1 × 10 mg (890717O-10mg)

製造商/商標名

Avanti Research - A Croda Brand 890717O

脂質類型

transfection
cationic lipids

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

Ethylphosphocholine (EPC) are amphiphilic cationic lipids containing hydrophilic headgroup and lipophilic tail.

生化/生理作用

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (14:1 EPC) is less toxic and is biodegradable. It is known to possess efficient DNA transfection activity. 14:1 EPC is very closely identical to the natural triacylglyceride lipids.

包裝

5 mL Clear Glass Sealed Ampule (890717O-10mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

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Mikhail A Galkin et al.
Journal of visualized experiments : JoVE, (134) (2018-04-24)
Detergents are indispensable for delivery of membrane proteins into 30-100 nm small unilamellar vesicles, while more complex, larger model lipid bilayers are less compatible with detergents. Here we describe a strategy for bypassing this fundamental limitation using fusogenic oppositely charged
Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery.
Jinjun Shi et al.
Angewandte Chemie (International ed. in English), 50(31), 7027-7031 (2011-06-24)
Rumiana Koynova et al.
The journal of physical chemistry. B, 111(27), 7786-7795 (2007-06-19)
Some mixtures of two cationic lipids including phospholipid compounds (O-ethylphosphatidylcholines) as well as common, commercially available cationic lipids, such as dimethylammonium bromides and trimethylammonium propanes, deliver therapeutic DNA considerably more efficiently than do the separate molecules. In an effort to
Boris G Tenchov et al.
Biochimica et biophysica acta, 1778(10), 2405-2412 (2008-08-30)
Synthetic cationic lipids can be used as DNA carriers and are regarded to be the most promising non-viral gene carriers. For this investigation, six novel phosphatidylcholine (PC) cationic derivatives with various hydrophobic moieties were synthesized and their transfection efficiencies for
Rumiana Koynova et al.
Biochimica et biophysica acta, 1768(2), 375-386 (2006-12-13)
Lipoplexes containing a mixture of cationic phospholipids dioleoylethylphosphatidylcholine (EDOPC) and dilauroylethylphosphatidylcholine (EDLPC) are known to be far more efficient agents in transfection of cultured primary endothelial cells than are lipoplexes containing either lipid alone. The large magnitude of the synergy

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