860488P

Safingol

Avanti Research^™ - A Croda Brand 860488P, powder

• 同義詞: L-threo-dihydrosphingosine (d18:0) z
• 經驗公式（希爾表示法）: C₁₈H₃₉NO₂
• CAS號碼: 15639-50-6
• 分子量：: 301.51
• 分類程式碼代碼: 12352211
• NACRES: NA.25

屬性

• 形狀: powder
• 包裝: pkg of 1 × 5 mg (860488P-5mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 860488P
• 脂質類型: sphingolipids; bioactive lipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: CCCCCCCCCCCCCCC[C@@](O)([H])[C@@]([H])(N)CO
• InChI: 1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3
• InChI 密鑰: OTKJDMGTUTTYMP-UHFFFAOYSA-N

描述

一般說明

Safingol is a synthetic L-threo-stereoisomer of endogenous (D-erythro-) sphinganine. It acts as an inhibitor of protein kinase C and sphingosine kinase in vitro. Safingol is involved in ceramide generation and induction of apoptosis. It is known to stimulate antitumor activity of cisplatin.

應用

Safingol has been used as a substituent of dihydrosphingosine (dhSph) to increase the cytotoxic response in N-(4-hydroxyphenyl)retinamide (4-HPR)-resistant cells.

包裝

5 mL Amber Glass Screw Cap Vial (860488P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable