857371P

VU0359595

(1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxamide, powder

• 同義詞: EVJ; VU0359595
• 經驗公式（希爾表示法）: C₂₅H₂₉BrN₄O₂
• CAS號碼: 1246303-14-9
• 分子量：: 497.43
• 分類程式碼代碼: 12352211
• NACRES: NA.25

屬性

• 化驗: >99% (TLC)
• 形狀: powder
• 包裝: pkg of 1 × 1 mg (857371P-1mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 857371P
• 脂質類型: bioactive lipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C

描述

一般說明

VU0359595 has been shown to selectively inhibit the PLD1 isoform at nM levels (see data below). **Images added as .gif in folder

應用

VU0359595 has been used as PLD2 (phospholipase D2) inhibitor to quantitatively address functional and molecular aspects of the involvement of PLD-derived phosphatidic acid (PA) in regulated exocytosis and as PLD1 inhibitor to treat the knockout mice to study its effects on them.

生化／生理作用

VU0359595 helps to block phospholipase D (PLD) which in turn reduces deoxyribonucleoside triphosphate (dNTP) biosynthesis in glioma models.

包裝

5 mL Amber Glass Screw Cap Vial (857371P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable