857135P

18:1 BMP (S,S)

sn-(3-oleoyl-2-hydroxy)-glycerol-1-phospho-sn-1′-(3′-oleoyl-2′-hydroxy)-glycerol (ammonium salt), powder

• 同義詞: lysobisphosphatidic acid; LBPA
• 經驗公式（希爾表示法）: C₄₂H₈₂NO₁₀P
• CAS號碼: 1246303-12-7
• 分子量：: 792.07
• 分類程式碼代碼: 51191904
• NACRES: NA.25

屬性

• 化驗: >99% (BMP (contains 30% positional isomers), TLC)
• 形狀: powder
• 包裝: pkg of 1 × 10 mg (857135P-10mg); pkg of 1 × 5 mg (857135P-5mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 857135P
• 脂質類型: cardiolipins; phospholipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: [H][C@](COP(OC[C@@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

描述

一般說明

Bis(monoacylglycerol) phosphate (BMP) is a phospholipid containing two-phosphate linked fatty acid esterified glycerol molecule. It is present in late endosome, majorly in intraluminal vesicles (ILVs) and is hydrolyzed by BMP hydrolase. BMP accounts to 15% of total organelle lipids.

應用

18:1 BMP (S,S) may be used as an external standard for calibration in ultra performance liquid chromatography-mass spectrometry (UPLC-MS) and as an internal standard in liquid chromatography - tandem mass spectrometer (LC-MS) for quantification of lipids from tissues.It may also be used in liposome preparation for dengue virus fusion studies.

生化／生理作用

Bis(monoacylglycerol)phosphate (BMP) plays a key role in cargo sorting and protein and lipid trafficking. The levels of BMP is elevated in lysosomal storage disorders (LSD) including Wolman disease, Niemann Pick disease and neuronal ceroid lipofuscinoses. It is resistant to degradation by the enzyme, acid phospholipase.

包裝

5 mL Clear Glass Sealed Ampule (857135P-10mg)

5 mL Clear Glass Sealed Ampule (857135P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3