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Key Documents

810283C

Avanti

TopFluor® PS

Avanti Polar Lipids 810283C

同義詞:

1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phospho-L-serine (ammonium salt)

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About This Item

經驗公式(希爾表示法):
C46H80BF2N4O10P
CAS號碼:
分子量::
928.93
分類程式碼代碼:
12352211

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (810283C-1mg)

製造商/商標名

Avanti Polar Lipids 810283C

濃度

1 mg/mL (810283C-1mg)

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

應用

TopFluor® PS may be used in liposome generation and as a synthetic fluorescent PS analogue to study PS distribution and dynamics in mouse embryonic fibroblasts (MEFs). It has also been used to study the fluorescence resonance energy transfer (FRET) efficiency between TopFluor PtdSer and RFP-K-RasG12V PBD mutants and to directly measure its interaction with RFP-K-RasG12V PBD mutant.

生化/生理作用

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It plays a key role in memory related issues and several other cognitive activities. PS actively participates in the locomotor functions. TopFluor-PS/1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phospho-l-serine is a synthetic fluorescent PS analog.

包裝

5 mL Amber Glass Screw Cap Vial (810283C-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


分析證明 (COA)

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存取文件庫

Lipid-Sorting Specificity Encoded in K-Ras Membrane Anchor Regulates Signal Output
Zhou Y, et al.
Cell, 168(1), 239-251 (2017)
Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies
Conrad KS, et al.
Nature Communications, 8(1908), 1-13 (2017)
Phosphatidylserine dynamics in cellular membranes
Kay JG, et al.
Molecular Biology of the Cell, 23(11), 2198-2212 (2012)
Adsorption of O-phospho-L-serine and L-serine onto poorly crystalline apatite
Benaziz L, et al.
Journal of Colloid and Interface Science, 238(1), 48-53 (2001)
Phosphoserine imprinted nanosensor for detection of Cancer Antigen 125
Buyuktiryaki S, et al.
Talanta, 167, 172-180 (2017)

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