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Key Documents

810185P

Avanti

TopFluor PI(4)P

Avanti Research - A Croda Brand 810185P, powder

同義詞:

1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-4-phosphate (ammonium salt)

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About This Item

經驗公式(希爾表示法):
C50H88BF2N5O17P2
CAS號碼:
分子量::
1142.01
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 50 μg (with stopper and crimp cap (810185P-50ug))

製造商/商標名

Avanti Research - A Croda Brand 810185P

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

Phosphatidylinositol 4-phosphate (PI4P) is a precursor of phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P2]. It is present in the membranes of Golgi apparatus.

應用

TopFluor PI(4)P has been used as fluorescently labeled phosphoinositide to examine phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) interaction with anionic lipids.

包裝

2 mL Amber Serum Vial with Stopper and Crimp Cap (810185P-50ug)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

No data available

閃點(°C)

No data available


分析證明 (COA)

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Xiaojun Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 32(7), 1732-1741 (2016-02-02)
Phosphatidylinositol phosphate (PIP) lipids are critical to many cell signaling pathways, in part by acting as molecular beacons that recruit peripheral membrane proteins to specific locations within the plasma membrane. Understanding the biophysics of PIP-protein interactions is critical to developing
Biophysical methods for the characterization of PTEN/lipid bilayer interactions
Harishchandra RK, et al.
Methods, 77, 125-135 (2015)
PI4P and PI (4, 5) P2 are essential but independent lipid determinants of membrane identity
Hammond GRV, et al.
Science, 337(6095), 727-730 (2012)

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