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重要文件

810253P

Avanti

脱氢麦角甾醇(DHE)

ergosta-5,7,9(11),22-tetraen-3β-ol, powder

同義詞:

DHE

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About This Item

經驗公式(希爾表示法):
C28H42O
CAS號碼:
分子量::
394.63
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (with stopper and crimp cap (810253P-1mg))

製造商/商標名

Avanti Research - A Croda Brand 810253P

運輸包裝

dry ice

儲存溫度

−70°C

SMILES 字串

O[C@H]1CC[C@]2(C(=CC=C3[C@H]4[C@@]([C@H](CC4)[C@H](C)\C=C\[C@@H](C(C)C)C)(CC=C32)C)C1)C

InChI

1S/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1

InChI 密鑰

QSVJYFLQYMVBDR-CMNOFMQQSA-N

一般說明

脱氢麦角固醇(DHE)是一种荧光固醇,具有与胆固醇相似的生物物理特性。它存在于酵母细胞和其他真菌中。

應用

脱氢麦角固醇(DHE)适用于将DHE从供体(LD)群体转移至受体(LA)脂质体。

生化/生理作用

脱氢麦角固醇(DHE)用于可视化细胞内运输和细胞内运输动力学。

包裝

2 mL 琥珀色血清小瓶(带有胶塞和钳口盖)(810253P-1 mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Reynold Homan et al.
Analytical biochemistry, 441(1), 80-86 (2013-07-16)
We describe a simple but sensitive fluorescence method to accurately detect the esterification activity of lecithin:cholesterol acyltransferase (LCAT). The new assay protocol employs a convenient mix, incubate, and measure scheme. This is possible by using the fluorescent sterol dehydroergosterol (DHE)
Molecular basis for sterol transport by StART-like lipid transfer domains
Horenkamp FA, et al.
The Embo Journal, 37(6) (2018)
Mohsen Pourmousa et al.
The journal of physical chemistry. B, 118(26), 7345-7357 (2014-06-04)
Although dehydroergosterol (DHE) is one of the most commonly used cholesterol (CHOL) reporters, it has remained unclear why it performs well compared with most other CHOL analogues and what its possible limitations are. We present a comprehensive study of the
Daniel Wüstner et al.
Microscopy research and technique, 74(1), 92-108 (2010-12-25)
Dehydroergosterol (DHE) is an intrinsically fluorescent sterol with absorption/emission in the ultraviolet (UV) region and biophysical properties similar to those of cholesterol. We compared the potential of UV-sensitive low-light-level wide-field (UV-WF) imaging with that of multiphoton (MP) excitation microscopy to
Olav Garvik et al.
Chemistry and physics of lipids, 159(2), 114-118 (2009-05-30)
The fluorescent sterol dehydroergosterol (DHE) is often used as a marker for cholesterol in cellular studies. We show by vesicle fluctuation analysis that DHE has a lower ability than cholesterol to stiffen lipid bilayers suggesting less efficient packing with phospholipid

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