推薦產品
描述
3β-hydroxy-5,24-cholestadiene
化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 10 mg (700060P-10mg)
pkg of 1 × 5 mg (700060P-5mg)
製造商/商標名
Avanti Research™ - A Croda Brand
運輸包裝
dry ice
儲存溫度
−20°C
InChI
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI 密鑰
AVSXSVCZWQODGV-DPAQBDIFSA-N
一般說明
与胆固醇相比,链甾醇缺少C24和C25之间的双键。它存在于精细胞和星形胶质细胞的细胞膜中,也是大脑主要固醇。
應用
链甾醇已作为甾醇用于测试与人类蛋白质Mincle的相互作用,并作为内部标准品用于超高效液相色谱-串联质谱(UHPLC-MS/MS)。它可以用于制备脂单层。
生化/生理作用
链甾醇是Bloch途径中的胆固醇前体,24-去氢胆固醇还原酶在此步骤中起催化作用。链甾醇在24-去氢胆固醇还原酶的损耗过程中累积,导致链甾醇化。链甾醇是肝X受体(LXR)激动剂。它是治疗神经退行性疾病的潜在靶点。链甾醇可调节巨噬细胞中的炎症信号。
包裝
5 mL 棕色玻璃螺旋盖小瓶 (700060P-10 mg)
5 mL 棕色玻璃螺旋盖小瓶 (700060P-5 mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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